Full list of publication:

Selected representative publications on the topic of

5) Others

  • Lio DCS, Chia RN, Kwek MSY, Wiraja C, Madden LE, Chang H, Khadir SMA, Wang X*, Becker DL*, Xu C*. Temporal Pressure Enhanced Topical Drug Delivery through Micropore Formation. Science Advances. 2020, 6(22), eaaz6919

4) Nucleic acid-based nanoparticles

  • C Wiraja, Y Mori, T Ichimura, J Hwang, C Xu*, JV Bonventre*. Continuous Nephrotoxicity Assessment on Kidney Tubuloids using Spherical Nucleic Acid-based mRNA Nanoflares. 2021.
  • Ponedal A, Zhu S, Sprangers A, Wang XQ, Yeo DC, Lio D, Zheng M, Capek M, Narayan S, Meckes B, Paller A*, Xu CJ*, Mirkin C*. Attenuation of abnormal scarring using spherical nucleic acids targeting transforming growth factor beta 1. ACS Applied Bio Materials 2020, 3(12), 8603.
  • Tanner EEL, Wiraja C, Curreri CA, Xu C*, Mitragotri S*. Stabilization and Topical Skin Delivery of Framework Nucleic Acids using Ionic Liquids. Advanced Therapeutics. 2020, 3(7), 2000041
  • Wiraja C, Zhu Y, Lio D, Yeo DC, Xie M, Fang W, Li Q, Zheng M, Van Steensel M, Wang L, Fan C*, Xu C*. Framework Nucleic Acids as Programmable Carrier for Transdermal Drug Delivery. Nature Communication, 2019, 10, 1147
  • Yeo DC, Wiraja C, Paller AS*, Mirkin CA*, Xu C*. Abnormal Scar Identification with Spherical Nucleic Acids Technology, Nature Biomedical Engineering, 2018, 2, 227

3) Microneedles

  • H Chang, SWT Chew, M Zheng, DCS Lio, C Wiraja, Y Mei, X Ning, M Cui, A Than, P Shi, D Wang, K Pu, P Chen, H Liu, C Xu*. Cryomicroneedles for Transdermal Cell Delivery. Nature Biomedical Engineering, 2021,
  • Ning X, Wiraja C, Lio DCS, Xu C*. A double layered microneedle platform fabricated through frozen spray-coating. Adv. Healthcare Mater. 2020, 9(10), 2000147
  • M Zheng, Z Wang, H Chang, L Wang, SWT Chew, DCS Lio, M Cui, L Liu, BCK Tee,* C Xu*. Osmosis-Powered Hydrogel Microneedles for Microliters of Skin Interstitial Fluid Extraction within Minutes. Adv. Healthcare Mater. 2020, 1901683.
  • Than A, Liu C, Chang H, Duong PK, Wang X*, Xu C*, Chen P*. Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery, Nature Communication, 2018, 9, 4433
  • Than A, Liang K, Xu S, Sun L, Duan H, Xi F, Xu C*, Chen P*. Obesity compounds to subcutaneous adipose tissue with polymeric microneedles patches. Small Methods. 2017, 1, 1700269
  • Chang H, Zheng M, Yu X, Than A, Seeni RZ, Kang R, Tian J, Khanh DP, Liu L, Chen P*, Xu C*. A swellable microneedle patch to rapidly extract skin interstitial fluid for timely metabolic analysis. Advanced Materials. 2017, 29 (37), 1702243
  • Tan C, Yeo D, Cao T, Tan VW, Srivastava R, Yow AP, Tan WP, Wong DW, Xu C, Tey HL*. Drug‐free microneedles in the treatment of keloids: a single‐blinded intra‐individual controlled clinical trial. Br J Dermatol. 2018, 179(6), 1418.
  • Yeo D, Balmayor E, Schantz JT, Xu C*. Microneedle Physical Contact as a Therapeutic for Abnormal Scars. European Journal of Medical Research, 2017, 22(1):28
  • Xue P, Yeo DCL, Chuah YJ, Kang YJ, Xu C*. Drug-eluting Microneedles for the Self-management of Keloids. Technology. 2014; 2(2): 144

2) Stem cell tracking

  • Wiraja C, Yeo DC, Tham KC, Chew SWT, Lim X, Xu C*. Real-Time Imaging of Dynamic Cell Reprogramming with Nanosensors, Small, 2018, 14, 1703440.
  • Fu J, Wiraja C, Chong R, Xu C*, Wang D*. Real-time and Non-invasive Monitoring of Embryonic Stem Cell Survival during the Development of Embryoid Bodies with Smart Nanosensor. Acta Biomaterialia, 2017, 49, 358–367
  • Pan J, Wiraja C, Zhao J, Zhang J, Li M, Zheng L, Xu C*. Nitric oxide nanosensors for predicting the development of osteoarthritis in rat model, ACS Applied Materials & Interfaces, 2017, 9(30), 25128-25137.
  • Gao Y, Lim J, Yeo D, Liao S, Lans M, Wang Y, Teoh SH, Goh BT, Xu C*, A selective and purification-free strategy for labeling adherent cell with inorganic nanoparticles, ACS Applied Materials & Interfaces, 2016, 8(10):6336
  • Wiraja C, Yeo D, Chong SK, Xu C*. Nanosensors for Continuous and Noninvasive Monitoring of Mesenchymal Stem Cell Osteogenic Differentiation. Small, 2016, 12(10):1342
  • Xu C, Miranda-Nieves D, Ankum J.A., Matthiesen M.E., Philips J.A., Roes I, Wojtkiewicz GR, Kultima JR, Zhao W, Vemular PK, Lin CP, Nahrendorf M., Karp JM*. Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticles Loaded Poly(lactide-co-glycolide) Microparticles. Nano Letters, 2012, 12(8):4131

1) Magnetic nanoparticles

  • Wang S, Guo X, Xiu W, Liu Y, Ren L, Xiao H, Yang F, Gao Y*, Xu CJ, Wang L*. Accelerating thrombolysis using a precision and clot-penetrating drug delivery strategy by nanoparticle-shelled microbubbles. Science advances 2020, 6(31): eaaz8204
  • Gao Y, Chan CU, Gu Q, Lin X, Zhang W, Yeo DCL, Alsema AM, Arora M, Chong MSK, Shi P, Ohl CD*, Xu CJ*, Controlled nanoparticle release from stable magnetic microbubble oscillations, NPG Asia Materials, 2016, 8, e260
  • Xu CJ, Yuan ZL, Kohler N, Kim JM, Chung MA, Sun SH*. FePt Nanoparticles as an Fe Reservoir for Controlled Fe Release and Tumor Inhibition. Journal of the American Chemical Society, 2009, 131(42): 15346
  • Xu CJ, Wang BD, Sun SH*. Dumbbell-like Au-Fe3O4 Nanoparticles for Target-Specific Platin Delivery. Journal of the American Chemical Society, 2009, 131(12): 4216
  • Xu CJ, Tung GA, Sun SH*. Size and Concentration Effect of Gold Nanoparticles on X-ray Attenuation As Measured on Computed Tomography. Chemistry of Materials, 2008, 20(13): 4167
  • Xu CJ, Xie J, Don H, Wang C, Kohler N, Walsh E, Morgan J, Chin YE, Sun SH*. Au-Fe3O4 Dumbbell Nanoparticles as Dual-Functional Probes. Angewandte Chemie International Edition, 2008, 47: 173
  • So MK, Xu CJ, Loening AM, Gambhir SS, Rao JH*. Self-illuminating quantum dot conjugates for in vivo imaging. Nature Biotechnology, 2006, 24(3): 339 (*Same Contribution)
  • Xu CJ, Xu K, Gu HW, Zheng RK, Liu H, Zhang XX, Guo Z, Xu B*. Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. Journal of the American Chemical Society, 2004, 126(32): 9938
  • Xu CJ, Xu K, Gu HW, Zhong X, Guo Z, Zheng RK, Zhang XX, Xu B*.  Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins. Journal of the American Chemical Society, 2004, 126(11): 3392